NAR Molecular Biology Database Collection entry number 114

http://metacyc.org/

Karp, P.D., Riley, M.

Bioinformatics Research Group SRI International Menlo Park, CA 94025, USA

Contact pkarp@ai.sri.com

MetaCyc is a metabolic-pathway database that describes 445 pathways and 1115 enzymes occurring in 158 organisms. MetaCyc is a review-level DB in that a given entry in MetaCyc often integrates information from multiple literature sources. The pathways in MetaCyc were determined experimentally, and are labeled with the species in which they are known to occur in based on literature references examined to date. MetaCyc contains extensive commentary and literature citations. Applications of MetaCyc include pathway analysis of genomes, metabolic engineering, and biochemistry education. MetaCyc is queried using the Pathway Tools graphical user interface, which provides a wide variety of query operations and visualization tools. MetaCyc is available through the WWW at URL http://ecocyc.org, and is available for local installation as a binary program for the PC and the Sun workstation, and as a set of flatfiles. Contact metacyc-info@ai.sri.com for information on obtaining MetaCyc.

79 new pathways have been added to MetaCyc in the past year, and a new PC version of MetaCyc coupled with the Pathway/Genome Navigator software is now available.

This work was supported by grant 1-R01-RR07861-01 from the Comparative Medicine Program at the National Center for Research Resources.

Go to the abstract in the NAR 2008 Database Issue.

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