NAR Molecular Biology Database Collection entry number 1158

http://www.mrc-lmb.cam.ac.uk/genomes/FlyTF/

Adryan, B. and Teichmann, S.A.

Theoretical and Computational Biology, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, United Kingdom

Contact boris@mrc-lmb.cam.ac.uk

FlyTF is a manually curated catalogue of Drosophila site-specific transcription factors (TFs). It integrates proteins identified as DNA-binding TFs by computational prediction based on structural domain assignments, and experimentally verified TFs from the literature. The data is available for case-by-case query (featuring a search form for various TF characteristics) and for bulk download.

We encourage the Drosophila community to provide feedback on our annotations. Future releases and updates to the database based on user feedback are planned, and the incorporation of the "12 Genomes" is underway. The FlyTF data is now available as "public bags" in FlyMine (http://www.flymine.org).

Work on FlyTF was enabled through an EMBO Longterm Fellowship to BA, and SAT is an EMBO Young Investigator.

1. Adryan, B. and Teichmann, S.A. (2006) FlyTF: a systematic review of site-specific transcription factors in the fruit fly Drosophila melanogaster. Bioinformatics 22(12): 1532
2. Adryan, B. and Teichmann, S.A. (2007). Computational Identification of Site-Specific Transcription Factors in Drosophila. Fly 1(3): 142

Go to the abstract in Bioinformatics

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